CAT 2 GENE PRODUCT
\sˌiːˌe͡ɪtˈiː tˈuː d͡ʒˈiːn pɹˈɒdʌkt], \sˌiːˌeɪtˈiː tˈuː dʒˈiːn pɹˈɒdʌkt], \s_ˌiː__ˌeɪ_t_ˈiː t_ˈuː dʒ_ˈiː_n p_ɹ_ˈɒ_d_ʌ_k_t]\
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A high-affinity, low capacity system y+ amino acid transporter with strong similarity to CATIONIC AMINO ACID TRANSPORTER, CAT-1. The two isoforms of the protein, CAT-2A and CAT-2B, exist due to alternative mRNA splicing. The transporter has specificity for the transport of ARGININE, LYSINE and ORNITHINE.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.