CALTHA VULGARIS

\kˈalθə vˈʌlɡɑːɹˌɪs], \kˈalθə vˈʌlɡɑːɹˌɪs], \k_ˈa_l_θ_ə v_ˈʌ_l_ɡ_ɑː_ɹ_ˌɪ_s]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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