BUTTON HOLE

\bˈʌtən hˈə͡ʊl], \bˈʌtən hˈə‍ʊl], \b_ˈʌ_t_ə_n h_ˈəʊ_l]\

Definitions of BUTTON HOLE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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