BAYR5417
\bˈe͡ɪ ˈɑː fˈa͡ɪv θˈa͡ʊzənd fˈɔːhˈʌndɹədən sˈɛvəntˌiːn], \bˈeɪ ˈɑː fˈaɪv θˈaʊzənd fˈɔːhˈʌndɹədən sˈɛvəntˌiːn], \b_ˈeɪ ˈɑː f_ˈaɪ_v θ_ˈaʊ_z_ə_n_d f_ˈɔː_h_ˈʌ_n_d_ɹ_ə_d_ə_n s_ˈɛ_v_ə_n_t_ˌiː_n]\
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A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.