B7 1 PROTEIN
\bˈiː sˈɛvən wˈɒn pɹˈə͡ʊtiːn], \bˈiː sˈɛvən wˈɒn pɹˈəʊtiːn], \b_ˈiː s_ˈɛ_v_ə_n w_ˈɒ_n p_ɹ_ˈəʊ_t_iː_n]\
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The natural ligand for the T-cell antigen CD28; (ANTIGENS, CD28); mediating T- and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and CTLA-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production.
By DataStellar Co., Ltd
