ATLANTAL ASPECT

\ɐtlˈantə͡l ˈaspɛkt], \ɐtlˈantə‍l ˈaspɛkt], \ɐ_t_l_ˈa_n_t_əl ˈa_s_p_ɛ_k_t]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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