ACTON BELL
\ˈaktən bˈɛl], \ˈaktən bˈɛl], \ˈa_k_t_ə_n b_ˈɛ_l]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.