ACRODERMATITIS

\ˌakɹə͡ʊdəmɐtˈa͡ɪtɪs], \ˌakɹə‍ʊdəmɐtˈa‍ɪtɪs], \ˌa_k_ɹ_əʊ_d_ə_m_ɐ_t_ˈaɪ_t_ɪ_s]\
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2010 - Medical Dictionary Database
By DataStellar Co., Ltd
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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